Are Psychedelic Drugs Addictive

Psychedelics are generally not considered addictive. This means that people do not become physically dependent on them and do not engage in compulsive drug-seeking behavior. They also do not experience withdrawal symptoms when they stop using psychedelics.

What Is Addiction?

The “Diagnostic and Statistical Manual of Mental Disorders” (DSM-5-TR) defines addiction as a chronic and relapsing condition characterized by compulsive drug seeking, continued use despite adverse consequences, and long-lasting changes to the brain.

However, some psychedelics, such as LSD, can produce tolerance. Tolerance means that a person has to keep taking higher doses of a substance to experience the same effects.

This can be potentially dangerous because the effects of the drug can be unpredictable.

LSD also creates a cross-tolerance to some other psychedelics, including psilocybin and mescaline. This means that if a person takes LSD, they would experience decreased effects if they took magic mushrooms.

What Do Psychedelics Do?

When people take psychedelic substances, they experience visual hallucinations. Changes in thinking and perception accompany these hallucinations. Euphoric moods, an altered sense of time, feelings of introspection, and spiritual experiences are also common.

Types of Psychedelics

• LSD: This psychedelic is clear or white and made from lysergic acid. It can cause profound changes in perception, mood, and cognition that can last as long as 12 hours.
• Psilocybin: This substance is found in certain types of hallucinogenic mushrooms.
• Mescaline: This substance is found in certain types of cactus, including peyote.
• DMT: This is a naturally-occurring psychedelic found in the nuts and barks of certain types of trees.

How Do Psychedelics Work

Psychedelic drugs impact the neural circuits in the brain that utilize the neurotransmitter serotonin, particularly those in the prefrontal cortex. Their action in this area of the brain leads to mood, perception, and cognition changes.

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